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Title: Glucosinolates, a natural chemical arsenal: More to tell than the myrosinase story
Authors: Abdel-Massih, Roula 
Debs, Esperance 
Othman, Leen
Attieh, Jihad 
Cabrerizo, Franco M.
Affiliations: College of Medicine, Central Michigan University, Mount Pleasant, MI, United States
Department of Biology 
Faculty of Medicine and Medical Sciences, University of Balamand, El-Koura, Lebanon
Department of Biology 
Instituto Tecnológico de Chascomús, National Scientific and Technical Research Council – National University of General San Martín, Chascomús, Argentina
Editors: Octavio L. Franco
Keywords: Antibacterial Activity
Chemical degradation
Glucosinolate hydrolysis products
Thermal degradation
Issue Date: 2023
Part of: Frontiers in Microbiology
Volume: 14
Glucosinolates are a group of thioglucosides that belong to the class of plant nitrogen-containing natural products. So far, very little biological activity has been associated with intact glucosinolates. The hydrolysis of glucosinolates has, for long, attracted attention because of the potent biological activity of the hydrolysis products. From allelopathic to antiparasitic, antimicrobial and antineoplastic effects, the activity spectrum of the degradation products of typical glucosinolates has been the subject of much research. The present review seeks to address the various means of glucosinolate degradation (thermal, enzymatic, or chemical degradation) and the ensuing products. It also aims to draw a comparative profile of the various antimicrobial effects of these degradation products to provide a further understanding of the biological function of these important compounds.
ISSN: 1664-302X
DOI: 10.3389/fmicb.2023.1130208
Open URL: Link to full text
Type: Journal Article
Appears in Collections:Department of Biology

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