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Title: Deregulation of ribosomal proteins in human cancers
Authors: El Khoury, Wendy
Nasr, Zeina 
Affiliations: Department of Biology 
Keywords: Cancer
Cell survival
Ribosomal proteins
Issue Date: 2021
Part of: Bioscience Reports
Volume: 41
Issue: 12
The ribosome, the site for protein synthesis, is composed of ribosomal RNAs (rRNAs) and ribosomal proteins (RPs). The latter have been shown to have many ribosomal and extraribosomal functions. RPs are implicated in a variety of pathological processes, especially tumorigenesis and cell transformation. In this review, we will focus on the recent advances that shed light on the effects of RPs deregulation in different types of cancer and their roles in regulating the tumor cell fate.
ISSN: 01448463
DOI: 10.1042/BSR20211577
Open URL: Link to full text
Type: Journal Article
Appears in Collections:Department of Biology

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