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Title: | Deregulation of ribosomal proteins in human cancers | Authors: | El Khoury, Wendy Nasr, Zeina |
Affiliations: | Department of Biology | Keywords: | Cancer Ribosomes Apoptosis Cell survival Metastasis Ribosomal proteins |
Issue Date: | 2021 | Part of: | Bioscience Reports | Volume: | 41 | Issue: | 12 | Abstract: | The ribosome, the site for protein synthesis, is composed of ribosomal RNAs (rRNAs) and ribosomal proteins (RPs). The latter have been shown to have many ribosomal and extraribosomal functions. RPs are implicated in a variety of pathological processes, especially tumorigenesis and cell transformation. In this review, we will focus on the recent advances that shed light on the effects of RPs deregulation in different types of cancer and their roles in regulating the tumor cell fate. |
URI: | https://scholarhub.balamand.edu.lb/handle/uob/5283 | ISSN: | 01448463 | DOI: | 10.1042/BSR20211577 | Open URL: | Link to full text | Type: | Journal Article |
Appears in Collections: | Department of Biology |
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