Please use this identifier to cite or link to this item: https://scholarhub.balamand.edu.lb/handle/uob/6936
Title: Effect of stem cell secretome in skin rejuvenation: a narrative review
Authors: Hani, Rita
Khayat, Luna
Rahman, Abir Abdel
Alaaeddine, Nada
Affiliations: Department of Medical Laboratory Sciences 
Keywords: Aging
Cell therapy
Growth factors
Mechanism of skin aging
Skin rejuvenation
Stem cell secretion
Issue Date: 2023-09-01
Publisher: Springer
Part of: Molecular Biology Reports
Volume: 50
Issue: 9
Start page: 7745
End page: 7758
Abstract: 
Cutaneous aging is an inevitable biological process that develops over time due to cumulative cellular and molecular changes caused by exposure to intrinsic (chronological aging) and extrinsic (photo-aging) factors on the skin. Skin aging is characterized by a decline in the body's capability to sustain senescence, dermal cell apoptosis, and homeostasis. Stem cell secretions (secretome) are defined as the total set of dynamically overlapping paracrine soluble growth factors, cytokines, chemokines, angiogenic factors, extracellular matrix proteins, and antimicrobial peptides known to be responsible for tissue rejuvenation, regeneration, homeostasis, and immunomodulation.
URI: https://scholarhub.balamand.edu.lb/handle/uob/6936
ISSN: 03014851
DOI: 10.1007/s11033-023-08622-y
Open URL: Link to full text
Type: Journal Article
Appears in Collections:Department of Medical Laboratory Sciences

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