Please use this identifier to cite or link to this item: https://scholarhub.balamand.edu.lb/handle/uob/5891
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dc.contributor.authorWehbe, Terek Wen_US
dc.contributor.authorAbi Chahine, Nassim Hen_US
dc.contributor.authorAnnous, Abdul-Rahman Aen_US
dc.contributor.authorFerri, Mohammad Aen_US
dc.contributor.authorBoulous, Robert Cen_US
dc.contributor.authorEl-Mestrah, Majid Fen_US
dc.date.accessioned2022-07-20T09:29:17Z-
dc.date.available2022-07-20T09:29:17Z-
dc.date.issued2017-
dc.identifier.issn2306-9759-
dc.identifier.urihttps://scholarhub.balamand.edu.lb/handle/uob/5891-
dc.description.abstractLiver cirrhosis represents a state of end-stage failure that is usually fatal. The condition results in liver dysfunction, recurrent ascites, encephalopathy, renal failure, splenomegaly, bleeding, and a poor quality of life in general. With the current severe shortage of donated organs, the only available treatment in the developing countries remains palliative care. We report a case of congenital metabolic liver cirrhosis due to glycogen storage disease diagnosed at age eight. The patient, a male, received bone marrow derived mononuclear cells (BMMC) at age 16 and again at age 17 with significant improvement of his biochemical liver function tests, ascites build-up, asthenia, splenomegaly and quality of life. Furthermore, liver biopsies showed clear reduction of the inflammation and fibrosis from Ishak score dropped from 3 to 1 paralleling the symptomatic improvement of the patient.en_US
dc.language.isoengen_US
dc.publisherNational Library of Medicineen_US
dc.subjectMononuclear stem cellsen_US
dc.subjectBone marrow cellsen_US
dc.subjectLiver cirrhosisen_US
dc.titleA case report of congenital glycogen storage liver cirrhosis treated with bone marrow derived stem cellsen_US
dc.typeJournal Articleen_US
dc.identifier.doi10.21037/sci.2017.07.04-
dc.identifier.pmid29057245-
dc.identifier.scopus2-s2.0-85042209676-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/85042209676-
dc.contributor.affiliationFaculty of Health Sciencesen_US
dc.description.volume4en_US
dc.description.issue9en_US
dc.date.catalogued2022-07-20-
dc.description.statusPublisheden_US
dc.identifier.openURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638994/en_US
dc.relation.ispartoftextStem Cell Investigationen_US
Appears in Collections:Department of Medical Laboratory Sciences
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