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Title: The association of vascular endothelial growth factor related SNPs and circulating iron levels might depend on body mass index
Authors: Chedid, Pia
Salami, Ali
Ibrahim, Mariam
Visvikis-Siest, Sophie
El Shamieh, Said
Affiliations: Faculty of Health Sciences 
Keywords: Body mass index
Iron levels
Vascular endothelial growth factor
Issue Date: 2022-01-18
Publisher: National Library of Medicine
Part of: Frontiers in Bioscience - Landmark
Volume: 27
Issue: 1
Vascular Endothelial Growth Factor (VEGF) is an essential regulator of vascular biology. In addition to the well-established role in angiogenesis, circulating VEGF levels were found elevated in severely anemic patients, pointing out that anemia might affect the progression of angiogenesis in malignant and benign diseases through the alteration of VEGF levels. Ten single nucleotide polymorphisms (SNPs) in VEGFA and other loci were shown to explain more than 50% of its circulating levels. This study investigated the association of those ten VEGF-related SNPs with serum iron levels in a general Lebanese population free of chronic diseases (N = 460).
ISSN: 27686701
DOI: 10.31083/j.fbl2701027
Open URL: Link to full text
Type: Journal Article
Appears in Collections:Department of Medical Laboratory Sciences

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