Please use this identifier to cite or link to this item: https://scholarhub.balamand.edu.lb/handle/uob/2616
Title: Synthesis and characterisation of poly (l-lactic acid) galactosyl derivatives : access to functionalised microspheres
Authors: Kassab, Rima 
Fenet, Bernard
Fessi, Hatem
Parrot-Loppez, Hélen
Affiliations: Department of Chemistry 
Keywords: Poly L-lactic acid
Galactosyl antennae
Covalent linkage
Microspheres
Issue Date: 2000
Part of: Tetrahedron letters
Volume: 41
Issue: 6
Start page: 877
End page: 881
Abstract: 
A new series of galactosyl-derived polymers has been used for the preparation of microspheres. The strategy is based on the modification of the terminal carboxylic group l-PLA (73.000) by coupling to a galactosyl antenna in the presence of the peptide coupling agents: DCC/HOBT. The degree of functionalisation varies between 60 and 70%, and antenna density between 1.74 and 2.78. The characterisations of the new products were carried out using 1H NMR, gel permeation chromatography, and acid base titration; the size of the functionalised microspheres was determined to be 210–270 μm by DLS.
URI: https://scholarhub.balamand.edu.lb/handle/uob/2616
DOI: 10.1016/S0040-4039(99)02216-9
Ezproxy URL: Link to full text
Type: Journal Article
Appears in Collections:Department of Chemistry

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