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|Title:||Synthesis and characterisation of poly (l-lactic acid) galactosyl derivatives : access to functionalised microspheres||Authors:||Kassab, Rima
|Affiliations:||Department of Chemistry||Keywords:||Poly L-lactic acid
|Issue Date:||2000||Part of:||Tetrahedron letters||Volume:||41||Issue:||6||Start page:||877||End page:||881||Abstract:||
A new series of galactosyl-derived polymers has been used for the preparation of microspheres. The strategy is based on the modification of the terminal carboxylic group l-PLA (73.000) by coupling to a galactosyl antenna in the presence of the peptide coupling agents: DCC/HOBT. The degree of functionalisation varies between 60 and 70%, and antenna density between 1.74 and 2.78. The characterisations of the new products were carried out using 1H NMR, gel permeation chromatography, and acid base titration; the size of the functionalised microspheres was determined to be 210–270 μm by DLS.
|URI:||https://scholarhub.balamand.edu.lb/handle/uob/2616||DOI:||10.1016/S0040-4039(99)02216-9||Ezproxy URL:||Link to full text||Type:||Journal Article|
|Appears in Collections:||Department of Chemistry|
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