Please use this identifier to cite or link to this item:
Title: Synthesis and characterisation of poly (l-lactic acid) galactosyl derivatives : access to functionalised microspheres
Authors: Kassab, Rima 
Fenet, Bernard
Fessi, Hatem
Parrot-Loppez, Hélen
Affiliations: Department of Chemistry 
Keywords: Poly L-lactic acid
Galactosyl antennae
Covalent linkage
Issue Date: 2000
Part of: Tetrahedron letters
Volume: 41
Issue: 6
Start page: 877
End page: 881
A new series of galactosyl-derived polymers has been used for the preparation of microspheres. The strategy is based on the modification of the terminal carboxylic group l-PLA (73.000) by coupling to a galactosyl antenna in the presence of the peptide coupling agents: DCC/HOBT. The degree of functionalisation varies between 60 and 70%, and antenna density between 1.74 and 2.78. The characterisations of the new products were carried out using 1H NMR, gel permeation chromatography, and acid base titration; the size of the functionalised microspheres was determined to be 210–270 μm by DLS.
DOI: 10.1016/S0040-4039(99)02216-9
Ezproxy URL: Link to full text
Type: Journal Article
Appears in Collections:Department of Chemistry

Show full item record


checked on May 1, 2021

Google ScholarTM


Dimensions Altmetric

Dimensions Altmetric

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.