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Title: Physicochemical characteristics, mutagenicity and genotoxicity of airborne particles under industrial and rural influences in Northern Lebanon
Authors: Melki, Pamela N.
Ledoux, Frédéric
Aouad, Samer 
Billet, Sylvain
Khoury, Bilal El 
Landkocz, Yann
Abdel-Massih, Roula
Courcot, Dominique
Affiliations: Department of Chemistry 
Department of Chemistry 
Department of Biology 
Keywords: PM2.5
Ames test
SOS Chromotest
Health effects
Subjects: Air--Pollution
Issue Date: 2017
Part of: Environmental science and pollution research
Volume: 24
Issue: 23
Start page: 18782
End page: 18797
In this work, the main objectives were to assess the mutagenic and genotoxic effects of fine particulate matter collected in an industrial influenced site in comparison with a non-industrial influenced one (rural site) and to relate the particulate matter (PM) composition to the observed genotoxic effects. At the industrial influenced site, higher concentrations of phosphates, trace metals, and polycyclic aromatic hydrocarbons (PAHs) in particles could be related to the contributions of quarries, fertilizer producer, cement plants, and tires burning. Gasoline and diesel combustion contributions were evidenced in particles collected at both sites. Particles collected under industrial influence showed a higher mutagenic potential on three tested strains of Salmonella typhimurium (TA98, YG1041, and TA102), and especially on the YG1041, compared to particles from the rural site. Furthermore, only particles collected in the vicinity of the industrial site showed a tendency to activate the SOS responses in Escherichia coli PQ37, which is indicative of DNA damage as a result of exposure of the bacteria cells to the action of mutagenic samples. The mutagenicity and genotoxicity of the industrial PM2.5–0.3 particulates may be attributed to its composition especially in organic compounds. This study showed that proximity of industries can affect local PM composition as well as PM genotoxic and mutagenic potential.
Ezproxy URL: Link to full text
Type: Journal Article
Appears in Collections:Department of Chemistry

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