Please use this identifier to cite or link to this item: https://scholarhub.balamand.edu.lb/handle/uob/7624
Title: A woman with mycosis fungoides, vitiligo, and a new hand nodule
Authors: Feghali, Joelle
Lavin, Leore
Ng, Spencer
Linos, Konstantinos
Geller, Shamir
Affiliations: Faculty of Medicine 
Keywords: Eccrine
Mycosis fungoides
Skin cancer
Skin of color (SOC)
Vitiligo
Issue Date: 2024-10-25
Part of: International Journal of Dermatology
Abstract: 
A 70-year-old African American female with a history of stage IV mycosis fungoides in remission presented with a gradually enlarging, red, ulcerated nodule on her right dorsal hand. The lesion was biopsied, and it showed intraepidermal proliferation with cytologic atypia and increased vasculature in the papillary dermis. Immunohistochemical staining indicated a yes-associated protein 1 (YAP1) rearrangement, confirmed by RNA sequencing, revealing a YAP1::MAML2 (mastermind-like transcriptional coactivator 2) fusion. The lesion was diagnosed as an eccrine porocarcinoma (EPC). The occurrence of EPCs following radiotherapy or trauma has been documented. This case highlights the importance of considering EPCs in patients with extensive skin treatments and immunosuppression history.
URI: https://scholarhub.balamand.edu.lb/handle/uob/7624
ISSN: 00119059
DOI: 10.1111/ijd.17552
Ezproxy URL: Link to full text
Type: Journal Article
Appears in Collections:Faculty of Medicine

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