Please use this identifier to cite or link to this item: https://scholarhub.balamand.edu.lb/handle/uob/7605
Title: Double the Trouble: A Rare Finding of Gastritis Cystica Profunda in a Previously Unoperated Young Female with Concomitant Helicobacter Pylori Infection
Authors: Haddad, Gaelle-Christie
Moussallem, Nicolas
Sbeih, Sergio
Karam, Karam
Fiani, Elias
Affiliations: Faculty of Medicine 
Faculty of Medicine 
Faculty of Medicine 
Faculty of Medicine 
Faculty of Medicine 
Keywords: Gastritis cystica profunda
Submucosal lesion
Upper gastrointestinal bleeding
Issue Date: 2024
Publisher: Pub Med
Part of: European Journal of Case Reports in Internal Medicine
Volume: 11
Issue: 10
Abstract: 
Gastritis cystica profunda (GCP) is a rare lesion of the stomach. It is characterised by hyperplasia and cystic dilation of the gastric gland in the submucosal layer. It is usually believed to occur at the site of previous gastric surgeries, as the anastomotic remnants act as a foundation for the development of the lesion. We present a case of a 39-year-old female, previously healthy with no history of gastric surgeries, who sought medical care for melena and lethargy of one month's duration. Her complete blood count showed a significant drop in haemoglobin (from 13 to 9 g/dl). Upper endoscopy revealed a submucosal lesion in the pre-pyloric region; biopsies showed the characteristic findings of GCP. The latter is a rare cause of upper gastrointestinal (GI) bleeding and its diagnosis and treatment remain challenging. Medical literature has not unveiled its association with chronic inflammation and Helicobacter pylori infection as many cases are being found in previously unoperated individuals. Even though GCP remains a rare entity, it should be incorporated in the differential diagnoses of upper GI bleeding and further prospective studies should highlight other contributing factors.
URI: https://scholarhub.balamand.edu.lb/handle/uob/7605
DOI: 10.12890/2024_004845
Open URL: Link to full text
Type: Journal Article
Appears in Collections:Faculty of Medicine

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