Please use this identifier to cite or link to this item: https://scholarhub.balamand.edu.lb/handle/uob/7512
Title: Screening for antibacterial activity of the extracts obtained from Ficus carica & Malva sylverstris on highly drug resistant bacteria
Authors: Dasuki, Ayah
Advisors: Abdou, Elias
Keywords: Antimicrobial resistance (AMR), Leaf extracts, Antibacterial activity, Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC), Gram-negative bacteria, Ficus carica, Malva sylvestris, Drug-resistant strains, In vitro experiments
Subjects: University of Balamand--Dissertations
Dissertations, Academic
Issue Date: 2024
Publisher: [Kalhat, Lebanon] : [University of Balamand], 2024
Abstract: 
Antimicrobial resistance (AMR) presents a pressing global health concern due to its
impact on morbidity, mortality, and healthcare expenses. As bacteria evolve resistance
mechanisms against conventional antibiotics, there is an urgent need to explore alternative
strategies to combat AMR. This study investigates the potential of plant medicine to address
AMR, focusing on the antibacterial activity of Ficus carica and Malva sylvestris ethanolic
extracts against highly drug-resistant gram-negative bacteria in Lebanon. Research for new
antibacterial compounds derived from plant sources is vital to counteract the increasing
ineffectiveness of synthetic drugs due to resistance. The investigation involved examining the
Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC)
of the leaf extracts. The MICs ranged between 40 and 160 mg/mL, and the majority of these
microorganisms were inhibited by 160 and 40 mg/mL of the ethanolic crude extracts.
Whereas, the MBC was most evident at 160 mg/mL and less at 80 mg/mL The results
demonstrated significant bactericidal and inhibitory activities of both plant extracts,
highlighting their potential as effective alternatives to conventional antibiotics.
Understanding the antibacterial properties of Ficus carica and Malva sylvestris could pave
the way for new and effective antimicrobial therapies, making these plants a promising
source of novel bioactive compounds in the fight against antibiotic resistance.
Description: 
Includes bibliographical references (p. 65-74)
URI: https://scholarhub.balamand.edu.lb/handle/uob/7512
Rights: This object is protected by copyright, and is made available here for research and educational purposes. Permission to reuse, publish, or reproduce the object beyond the personal and educational use exceptions must be obtained from the copyright holder
Type: Thesis
Appears in Collections:UOB Theses and Projects

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