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Title: | How to tackle therapeutic inertia in heart failure with reduced ejection fraction. A scientific statement of the Heart Failure Association of the ESC | Authors: | Savarese, Gianluigi Lindberg, Felix Cannata, Antonio Chioncel, Ovidiu Stolfo, Davide Musella, Francesca Tomasoni, Daniela Abdelhamid, Magdy Banerjee, Debasish Bayes-Genis, Antoni Berthelot, Emmanuelle Braunschweig, Frieder Coats, Andrew J S Girerd, Nicolas Jankowska, Ewa A Hill, Loreena Lainscak, Mitja Lopatin, Yury Lund, Lars H Maggioni, Aldo P Moura, Brenda Rakisheva, Amina Ray, Robin Seferovic, Petar M Skouri, Hadi Vitale, Cristiana Volterrani, Maurizio Metra, Marco Rosano, Giuseppe M C |
Affiliations: | Faculty of Medicine | Keywords: | Clinical inertia Guidelines‐directed medical therapy Heart failure Heart failure with reduced ejection fraction Implementation |
Issue Date: | 2024-05-22 | Publisher: | National Library Medicine | Part of: | European Journal of Heart Failure | Abstract: | Guideline-directed medical therapy (GDMT) in patients with heart failure and reduced ejection fraction (HFrEF) reduces morbidity and mortality, but its implementation is often poor in daily clinical practice. Barriers to implementation include clinical and organizational factors that might contribute to clinical inertia, i.e. avoidance/delay of recommended treatment initiation/optimization. The spectrum of strategies that might be applied to foster GDMT implementation is wide, and involves the organizational set-up of heart failure care pathways, tailored drug initiation/optimization strategies increasing the chance of successful implementation, digital tools/telehealth interventions, educational activities and strategies targeting patient/physician awareness, and use of quality registries. This scientific statement by the Heart Failure Association of the ESC provides an overview of the current state of GDMT implementation in HFrEF, clinical and organizational barriers to implementation, and aims at suggesting a comprehensive framework on how to overcome clinical inertia and ultimately improve implementation of GDMT in HFrEF based on up-to-date evidence. |
URI: | https://scholarhub.balamand.edu.lb/handle/uob/7394 | ISSN: | 13889842 | DOI: | 10.1002/ejhf.3295 | Ezproxy URL: | Link to full text | Type: | Journal Article |
Appears in Collections: | Faculty of Medicine |
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