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Title: Epidemiology of pathogens causing acute diarrhea in patients presenting to the emergency departments in 4 hospitals in Lebanon
Authors: Helou, Mariana
Nasr, Janane
Hajjar, Micheline
Bourji, Alaa
Feghaly, Rita
Jabbour, Elsy
Abboud, Edmond
Abboud, Emma
Mahdi, Ahmad
Mina, Jonathan
Asmar, Alain
Husni, Rola
Affiliations: Faculty of Medicine 
Issue Date: 2024-03-01
Part of: Medicine (United States)
Volume: 103
Issue: 9
Acute diarrhea is a prevalent disease worldwide and a cause of mortality in low and middle-income countries. In previous studies, the causative enteropathogen is found in 38% to 58% of patients, leaving a considerable diagnostic gap. In this study, we intend to determine the pathogenic agents responsible for acute diarrhea in patients presenting to the Emergency Departments of several Lebanese hospitals. A total of 100 stool samples were collected between June 2022 and June 2023 from patients presenting with acute diarrhea to the Emergency Departments. Pathogens were detected by multiplex polymerase chain reaction. The average age for the patients was 53 years old. All patients presented with diarrhea, 15 of them had fever associated. In total, 46 patients were admitted to the hospital (70%), among them 80% received Intravenous antibiotics. Campylobacter was the most common agent detected in 36%, followed by Rotavirus 19%, and Noroviruses 15%. The rest was detected at lower percentages. Bacteria accounted for 49% of cases, viruses for 39%, and parasitic infection 6%. Acute diarrhea epidemiology is understudied in Lebanon. This study is the first Lebanese data about acute diarrhea pathogens. Avoiding overuse of antibiotics in bacterial versus viral infections can be achieved while prevention campaigns can raise awareness about food and water safety at the community level.
DOI: 10.1097/MD.0000000000037316
Open URL: Link to full text
Type: Journal Article
Appears in Collections:Faculty of Medicine

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