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Title: Barriers toward xenotransplantation in Arab World
Authors: Ghazi, Maya
Saleh, Aalaa
Abdallah, Malak
El Masri, Diala
El Masri, Jad
El Ayoubi, Lemir Majed
Hawi, Jihad 
Jurjus, Abdo
Affiliations: Faculty of Medicine 
Keywords: Arab countries
Issue Date: 2024
Part of: Xenotransplantation
Volume: 31
Issue: 2
Organ transplant is a crucial therapeutic strategy offering a life-saving and transformative medical intervention. It provides an opportunity to improve their quality of life and increase their lifespan. The shortage of organs remains a critical global challenge, leading to a prolonged waiting times for organ receivers, which contributes to an increase in morbidity and mortality rates. Hence, xenotransplantation offered a promising solution to the global shortage of organs through the use of animal organs, leading to an increase in donor availability, reducing waiting times, minimizing organ trafficking, improving genetic engineering advancements, and driving scientific innovation. Even though xenotransplantation has many benefits in the clinical setting, it has many barriers that are hindering its achievements and constraining its occurrence. Some barriers to xenotransplant are general, such as the immunological barrier, while others are specific to certain regions due to local causes. The Arab region exhibits disparities in clinical settings compared to the global context, marked by the huge economic crisis and a shortage of trained healthcare professionals. Considering the huge resources and advancements needed in the field of xenotransplantation, this review aims to explore the specific barriers toward xenotransplantation in the Arab countries, highlighting the challenges to overcome these barriers.
ISSN: 0908665X
DOI: 10.1111/xen.12852
Ezproxy URL: Link to full text
Type: Journal Article
Appears in Collections:Faculty of Medicine

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