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Title: Biomarkers of chronic traumatic encephalopathy: A state-of-the art review
Authors: Gerges, Jennifer Abi
Chalhoub, Issam
Atallah, Carl
Khoury, Rita
Affiliations: Faculty of Medicine 
Keywords: Biomarker
Cerebrospinal fluid
Chronic Traumatic Encephalopathy
Traumatic encephalopathy syndrome
Issue Date: 2023-06
Publisher: Elsevier
Part of: Biomarkers in Neuropsychiatry
Volume: 8
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative condition that occurs several years following repetitive mild concussive or sub concussive brain injuries. To date, it is a post-mortem diagnosis. Traumatic encephalopathy syndrome (TES) is a framework that was developed as a clinical predictor of CTE in living individuals. Development of biomarkers of CTE, detectable through imaging or bodily fluids will aid improve the diagnostic accuracy of CTE in life, and help develop prevention and therapeutic strategies. This article reviews biomarkers investigated to date, and discusses challenges and future avenues in this burgeoning field.
DOI: 10.1016/j.bionps.2023.100066
Ezproxy URL: Link to full text
Type: Journal Article
Appears in Collections:Faculty of Medicine

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