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Title: Role of circulating tumor DNA and circulating tumor cells in breast cancer: History and updates
Authors: Chedid, Julien
Allam, Sabine
Chamseddine, Nathalie
Bou Zerdan, Maroun
El Nakib, Clara
Assi, Hazem I
Affiliations: Faculty of Medicine 
Keywords: Circulating tumor DNA
Breast cancer
Cell-free DNA
Circulating tumor cells
Issue Date: 2022-02-23
Publisher: National Library of Medicine
Part of: SAGE Open Medicine
Volume: 10
Circulating tumor DNA, cell-free DNA, and circulating tumor cells have been at the epitome of recent research in breast cancer. These forms of liquid biopsies have been used in monitoring disease progression, estimating the risk of relapse, and response to treatment. Much has been done in relation to serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease. Some studies have also explored their use in monitoring treatment response. As the field of liquid biopsies expands, more prospective studies are needed to tailor management in an individualistic approach. In this literature review, the authors explore the multiple uses of circulating tumor DNA and circulating tumor cells in breast cancer.
ISSN: 2050-3121
DOI: 10.1177/20503121221077838
Open URL: Link to full text
Type: Journal Article
Appears in Collections:Faculty of Medicine

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