UOBScholar Hub
UOB Libraries created the UOBScholar Hub, an Institutional Repository (IR) for archiving and collecting all the research output of the UOB community. It aims to improve the visibility, usage and impact of research conducted at UOB. Materials included are: academic journal articles, conference papers and presentations, books and book chapters, ongoing research papers, reports and patents.
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https://scholarhub.balamand.edu.lb/handle/uob/6210| Title: | AhRR methylation contributes to disease progression in urothelial bladder cancer | Authors: | El-Haddad, Nataly W El Kawak, Michelle El Asmar, Khalil Jabbour, Michel E Moussa, Mohamad A Habib, Rima R Dhaini, Hassan R |
Affiliations: | Faculty of Medicine | Keywords: | FGFR3 Urothelial bladder cancer Methylation Muscle-invasiveness p53 Tobacco smoking |
Issue Date: | 2022-10-12 | Publisher: | National Library of Medicine | Part of: | Cancer biomarkers : section A of Disease markers | Volume: | 35 | Issue: | 2 | Start page: | 167 | End page: | 177 | Abstract: | Bladder Cancer (BCa) is the tenth most incident malignancy worldwide. BCa is mostly attributed to environmental exposure and lifestyle, particularly tobacco smoking. The Aryl Hydrocarbon Receptor Repressor (AhRR) participates in the induction of many enzymes involved in metabolizing carcinogens, including tobacco smoke components. Additionally, studies have shown that smoking demethylates the (AhRR) gene in blood, suggesting AhRR demethylation as a specific serum smoking biomarker. |
URI: | https://scholarhub.balamand.edu.lb/handle/uob/6210 | DOI: | 10.3233/CBM-220002 | Open URL: | Link to full text | Type: | Journal Article |
| Appears in Collections: | Faculty of Medicine |
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