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Title: The association between psychotic experiences and health-related quality of life: a cross-national analysis based on World Mental Health Surveys
Authors: Alonso, Jordi
Saha, Sukanta
Lim, Carmen C W
Aguilar-Gaxiola, Sergio
Al-Hamzawi, Ali
Benjet, Corina
Bromet, Evelyn J
Degenhardt, Louisa
de Girolamo, Giovanni
Esan, Oluyomi
Florescu, Silvia
Gureje, Oye
Haro, Josep M
Hu, Chiyi
Karam, Elie G.
Karam, Georges
Kovess-Masfety, Viviane
Lepine, Jean-Pierre
Lee, Sing
Mneimneh, Zeina
Navarro-Mateu, Fernando
Posada-Villa, Jose
Sampson, Nancy A
Scott, Kate M
Stagnaro, Juan Carlos
Ten Have, Margreet
Viana, Maria Carmen
Kessler, Ronald C
McGrath, John J
Affiliations: Faculty of Medicine 
Keywords: Health-related quality of life
Perceived health
Psychotic experiences
Social network burden
World Mental Health surveys
Issue Date: 2018
Publisher: Elsevier
Part of: Schizophrenia Research
Volume: 201
Start page: 46
End page: 53
Psychotic experiences (PEs) are associated with a range of mental and physical disorders, and disability, but little is known about the association between PEs and aspects of health-related quality of life (HRQoL). We aimed to investigate the association between PEs and five HRQoL indicators with various adjustments. Using data from the WHO World Mental Health surveys (n = 33,370 adult respondents from 19 countries), we assessed for PEs and five HRQoL indicators (self-rated physical or mental health, perceived level of stigma (embarrassment and discrimination), and social network burden). Logistic regression models that adjusted for socio-demographic characteristics, 21 DSM-IV mental disorders, and 14 general medical conditions were used to investigate the associations between the variables of interest. We also investigated dose-response relationships between PE-related metrics (number of types and frequency of episodes) and the HRQoL indicators. Those with a history of PEs had increased odds of poor perceived mental (OR = 1.5, 95% CI = 1.2-1.9) and physical health (OR = 1.3, 95% CI = 1.0-1.7) after adjustment for the presence of any mental or general medical conditions. Higher levels of perceived stigma and social network burden were also associated with PEs in the adjusted models. Dose-response associations between PE type and frequency metrics and subjective physical and mental health were non-significant, except those with more PE types had increased odds of reporting higher discrimination (OR = 2.2, 95% CI = 1.3-3.5). Our findings provide novel insights into how those with PEs perceive their health status.
ISSN: 09209964
DOI: 10.1016/j.schres.2018.04.044
Ezproxy URL: Link to full text
Type: Journal Article
Appears in Collections:Faculty of Medicine

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