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Title: Histamine, paroxysmal AV block and low adenosine syncope a case report
Authors: Wansa, Nader
Goethals, Peter
DeRoy, Luc
Affiliations: Faculty of Medicine 
Keywords: Histamine overload
Hypersensitive adenosine receptors
Low adenosine syncope
Paroxysmal idiopathic atrioventricular block
Issue Date: 2018
Part of: Journal of Electrocardiology
Volume: 51
Issue: 1
Start page: 150
End page: 152
Histamine is a widespread natural amine, rarely suspected to provoke syncope due to complete atrio-ventricular block. A patient was admitted to the emergency room after an episode of vomiting and syncope following a dinner of mussels, most likely attributable to a histamine food intoxication. Stale mussels are ostensibly known to occasionally encompass high concentrations of histamine. We hereby present, a documented unexpected complete atrioventricular block (AV block) with preserved stable sinus electrical activity during an episode of fainting with vomiting. Pathophysiologically, we hypothesize a possible intense H1 and/or A1 receptor stimulation linked to histamine overload, suggestive of a variant of idiopathic AVB or low adenosine syncope.
ISSN: 00220736
DOI: 10.1016/j.jelectrocard.2017.09.003
Ezproxy URL: Link to full text
Type: Journal Article
Appears in Collections:Faculty of Medicine

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