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Title: Ovulation induction with gonadotropins
Authors: Delbaere, Anne
Bruyneel, Aude
Papas, Ralph
Affiliations: Faculty of Medicine 
Keywords: Anovulatory disorder
Assisted reproductive technologies (ART)
Controlled ovarian hyperstimulation
Follicle stimulating hormone (FSH)
Gonadotropin-releasing hormone (GnRH)
Human chorionic gonadotropin (hCG)
In vitro gertilization (IVF)
Intra-uterine insemination (IUI)
Luteinizing hormone (LH)
Ovarian hyperstimulation syndrome (OHSS)
Ovarian reserve
Ovulation induction
Issue Date: 2018
Part of: Encyclopedia of Endocrine Diseases
Start page: 570
End page: 580
Gonadotropins have been available for clinical use for > 60 years for many conditions in the field of reproductive medicine. The article provides an overview of the pioneering work leading to the wide range of pharmaceutical gonadotropin preparations currently available. It underlines the major difference between ovulation induction intended to restore normal ovulation and promote monofollicular development in anovulatory patients and controlled ovarian hyperstimulation intended to induce a multi-follicular ovulation in infertile patients, often ovulatory, in order to increase their chance of conception. Different treatment regimens are addressed that are intended to avoid major side-effects, such as high-order multiple pregnancies and OHSS.
ISBN: 9780128122006
DOI: 10.1016/B978-0-12-801238-3.65169-3
Type: Book Chapter
Appears in Collections:Faculty of Medicine

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