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Title: Identification and management of Lynch syndrome in the Middle East and North African countries: outcome of a survey in 12 countries
Authors: Sina, Mohammad
Ghorbanoghli, Zeinab
Abedrabbo, Amal
Al-Mulla, Fahd
Sghaier, Rihab Ben
Buisine, Marie-Pierre
Cortas, George
Goshayeshi, Ladan
Hadjisavvas, Andreas
Hammoudeh, Wail
Hamoudi, Waseem
Jabari, Carol
Loizidou, Maria A
Majidzadeh-A, Keivan
Marafie, Makia J
Muslumov, Gurbankhan
Rifai, Laila
Seir, Rania Abu
Talaat, Suzan M
Tunca, Berrin
Ziada-Bouchaar, Hadia
Velthuizen, Mary E
Sharara, Ala I
Ahadova, Aysel
Georgiou, Demetra
Vasen, Hans F A
Affiliations: Faculty of Medicine 
Keywords: Colorectal cancer
Lynch syndrome
Middle Eastern countries
North African countries
Issue Date: 2021
Publisher: Springer
Part of: Familial Cancer
Volume: 20
Issue: 3
Start page: 215
End page: 221
Lynch syndrome (LS), the most common inherited form of colorectal cancer (CRC), is responsible for 3% of all cases of CRC. LS is caused by a mismatch repair gene defect and is characterized by a high risk for CRC, endometrial cancer and several other cancers. Identification of LS is of utmost importance because colonoscopic surveillance substantially improves a patient's prognosis. Recently, a network of physicians in Middle Eastern and North African (ME/NA) countries was established to improve the identification and management of LS families. The aim of the present survey was to evaluate current healthcare for families with LS in this region.
ISSN: 13899600
DOI: 10.1007/s10689-020-00211-3
Open URL: Link to full text
Type: Journal Article
Appears in Collections:Faculty of Medicine

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