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Title: Aplastic anemia secondary to dual cancer immunotherapies a physician nightmare: case report and literature review
Authors: Younan, Romy G
Raad, Roy A
Sawan, Bassem Y
Said, Rabih
Affiliations: Faculty of Medicine 
Faculty of Medicine 
Faculty of Medicine 
Keywords: ATG
Anti-Thymocyte Globulin
Issue Date: 2021
Publisher: BMC
Part of: Allergy, Asthma & Clinical Immunology
Volume: 17
Issue: 1
Start page: 1
End page: 5
Treatment with immune checkpoint inhibitors has revolutionized cancer treatment over the past several years. Despite their clinical benefits, a wide range of immune-mediated toxicities can be observed including hematological toxicities. Although, the majority can easily be managed, immune-mediated adverse events rarely can be severe and difficult to approach. Herein, we are reporting a case of very severe aplastic anemia secondary to ipilimumab (I) and nivolumab (N) treatment that failed various treatment including intensive immune suppressive therapy.
ISSN: 1710-1484
DOI: 10.1186/s13223-021-00616-4
Open URL: Link to full text
Type: Journal Article
Appears in Collections:Faculty of Medicine

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