Please use this identifier to cite or link to this item:
Title: Spectroscopic and thermodynamic studies of the inclusion complexation of thiourea substrate with hydroxypropyl- β -cyclodextrin
Authors: Hassan, Inas EL
Allouch, Ahmad
Abou Dalle, Adib
Nakat, Hanna El 
Omar, Fawaz El
Affiliations: Department of Chemistry 
Keywords: Thiourea
Inclusion complexes
Association constant
Issue Date: 2013
Part of: Chemical science transactions journal
Volume: 2
Issue: 4
Start page: 1475
End page: 1481
A simple and fast spectrophotometric method has been used to determine the thermodynamic parameters of the inclusion complex formed between N-(2-ethylphenyl)-N'-(2- methylphenyl) thiourea, a hydrophobic substrate trap and hydroxypropyl-β-cyclodextrin (HP−β−CD). The overall association constants have been calculated at different temperatures using the Scott's method and are found to decrease with increase in temperature. The free energy change (∆G°) and the enthalpy of formation (∆H°) as well as the entropy (∆S°) have been determined for the various inclusions. The method has been applied with satisfactory precision; the values of relative standard deviations did not exceed 2%.
Open URL: Link to full text
Type: Journal Article
Appears in Collections:Department of Chemistry

Show full item record

Record view(s)

checked on Oct 23, 2021

Google ScholarTM


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.