Please use this identifier to cite or link to this item: https://scholarhub.balamand.edu.lb/handle/uob/2259
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dc.contributor.authorWehbe, Nadineen_US
dc.contributor.authorPatra, Digambaraen_US
dc.contributor.authorAbdel-Massih, Roulaen_US
dc.contributor.authorBaydoun, Elias A-H.en_US
dc.date.accessioned2020-12-23T09:09:39Z-
dc.date.available2020-12-23T09:09:39Z-
dc.date.issued2019-
dc.identifier.urihttps://scholarhub.balamand.edu.lb/handle/uob/2259-
dc.description.abstractDevelopment of nanomaterials has drawn interest on silver nanoparticles (AgNPs), which are being incorporated in several biomedical and environmental applications, especially anti-bacterial properties of AgNPs has intense excitement for their commercial use. However, the impact of AgNPs on cell membranes, such as phospholipid membrane properties, is not clearly understood yet. By applying curcumin as a probe molecule, this work was done for the first time to investigate the effect of AgNPs on membrane properties, such as permeability and phase transition temperature using 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes as a model for phospholipid membranes. We concluded that AgNPs at low concentration decrease the partition of curcumin into DMPC liposomes by ∼4-fold. In the presence of AgNPs, curcumin was found to be located close to the stern layer of DMPC liposomes by using a hydrophobic quencher, cetylpyridinium bromide (CPB). In addition, AgNPs broadened the phase transition temperature of DMPC liposomes, which ranged from 20 °C to 35 °C.en_US
dc.language.isoengen_US
dc.subjectAgNPsen_US
dc.subjectLiposomesen_US
dc.subjectDMPCen_US
dc.subjectCurcuminen_US
dc.subjectPermeabilityen_US
dc.subjectPhase transitionen_US
dc.subjectProbeen_US
dc.titleModulation of membrane properties by silver nanoparticles probed by curcumin embedded in 1,2-Dimyristoyl-sn-glycero-3-phosphocholine liposomesen_US
dc.typeJournal Articleen_US
dc.identifier.doi10.1016/j.colsurfb.2018.09.053-
dc.contributor.affiliationDepartment of Biologyen_US
dc.description.volume173en_US
dc.description.startpage94en_US
dc.description.endpage100en_US
dc.date.catalogued2019-09-04-
dc.description.statusPublisheden_US
dc.identifier.ezproxyURLhttp://ezsecureaccess.balamand.edu.lb/login?url=https://doi.org/10.1016/j.colsurfb.2018.09.053en_US
dc.identifier.OlibID198566-
dc.relation.ispartoftextJournal of colloids and surfaces B: biointerfacesen_US
dc.provenance.recordsourceOliben_US
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