Leptine, insuline, IGF-1 et masse osseuse chez des adolescentes sédentaires

Abstract

AIM OF THE STUDY : To investigate the relationships between serum leptin, IGF-1, insulin and bone mineral content and density in a group of Lebanese sedentary adolescent girls. ME T H O D S A N D R E S U L T S : Twenty Lebanese sedentary adolescent girls participated in our study. Total body bone mineral content and density were measured by dual-energy X-ray absorptiometry (DEXA). In parallel, fasting leptin, IGF-1 and insulin concentrations were also measured. Serum leptin, IGF-1 and insulin concentrations were not associated with total body bone mineral content (BMC), total body bone mineral density (BMD) or pelvis BMD. CONCLUSION: Serum leptin, IGF-1 and insulin concentrations are not positive predictors of total body bone mineral content or density in this study group.