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dc.contributor.authorDhaini, Hassanen_US
dc.contributor.authorNassif, Rana Men_US
dc.description.abstractBisphenol A (BPA) is a commonly used monomer in various products including bottled water. Numerous studies have reported endocrine adverse effects and neoplasia associated with BPA exposure in animals. However, considerable discrepancies exist among these studies with respect to both the nature of the toxic effects and the threshold dose. In Lebanon, 19-L polycarbonate (PC) bottles of drinking water are widely used in urban areas. The present study aims at assessing BPA human exposure and associated health risks from drinking water in Lebanese. A total of 22 bottled water sources, packaged in PC, were identified from licensed and non-licensed sources. Water samples were analyzed following exposure to sunlight for 72 h. BPA in water was quantified by HPLC, and other potential organic pollutants were screened by GC/MS. Fifty-nine percent of samples showed BPA levels above detection limits (>0.05 ng/mL). The median BPA level was 0.1 ng/mL (range 0.05 to 1.37 ng/mL). The mean BPA level for the total number of samples was 0.169 ng/mL (±0.280). A higher mean BPA level was found in water from licensed companies compared to non-licensed sources, however, not statistically significant. Screening showed the presence of dibutyl-phthalate and dioctyl-phthalate in only two samples. Endocrine disruptors (EDR) are ubiquitous contaminants in bottled water in Lebanon with potential health risk implications. Although estimated exposure levels are below the reference dose (RfD), further studies are needed to quantitate exposure from various sources and to investigate EDR contribution to existing epidemics in the country.en_US
dc.format.extent8 p.en_US
dc.subjectEndocrine disruptors (EDR)en_US
dc.subjectBisphenol A (BPA)en_US
dc.subjectDrinking wateren_US
dc.subject.lcshRisk assessmenten_US
dc.titleExposure assessment of endocrine disruptors in bottled drinking water of Lebanonen_US
dc.typeJournal Articleen_US
dc.contributor.affiliationDepartment of Medical Laboratory Sciencesen_US
dc.contributor.affiliationDepartment of Medical Laboratory Sciencesen_US
dc.relation.ispartoftextJournal of environmental monitoring and assessmenten_US
Appears in Collections:Department of Medical Laboratory Sciences
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