Comparative x-ray single crystal study of acetylated-β-D-galactopyranosyls azide and isothiocyanat

Abstract

The structures of two peracetylated p-D-galactopyranosides substituted at theanomeric C atom with either an isothiocyanate or an azide group, have been determinedby single crystal X-ray diffraction analysis. The two compounds show very similarmolecular conformation, except for the substituent groups at the anomeric C atom andfor the acetyl groups of the 06 atoms. They crystallize in different infinite chain-typestructures. While the isothiocyanate group extends in a large intermolecular space, theazide group is placed in a more crowded environment.