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dc.contributor.advisorKaram, Marcen_US
dc.contributor.authorAbboud, Andrewen_US
dc.descriptionIncludes bibliographical references (p. 34-36)en_US
dc.description.abstractPain is a worldwide health problem that can affect the quality of life and result in psychological, physical, and social consequences. Hyperalgesia is an increased sensitivity to feeling pain and an extreme response to pain. Bee Venom (BV) from the honeybee can help in the treatment of hyperalgesia by reducing its nociceptive behavior. Formalin is the pain-inducing agent used in this research. The hot plate test is used to measure the hot plate latency of mice. In this study, the effect of bee venom on the hot-plate latency related to hyperalgesia and whether BV alone or BV combined with formalin provides the most efficient anti-nociceptive treatment for hyperalgesia were investigated. A 100 μl injection of BV was given to each mouse in the BV group and the formalin+BV group at a dose of 0.1 mg/kg. The formalin group and the formalin+BV group each received a subcutaneous injection of 50 μl of 5% formalin into the left hind paw 30 minutes following the BV injection. One-way ANOVA was carried out using Prism 9 software to compare the hot plate latencies between the four groups as a function of injection time and at each individual time point. The findings of this study indicated that BV might be an effective anti-nociceptive treatment for hyperalgesia. However, it has been demonstrated that formalin and BV operate more effectively together than BV does alone to produce a long-lasting anti-nociceptive effect.en_US
dc.description.statementofresponsibilityby Andrew Abbouden_US
dc.format.extent1 online resource (viii, 43 pages) : ill., tablesen_US
dc.rightsThis object is protected by copyright, and is made available here for research and educational purposes. Permission to reuse, publish, or reproduce the object beyond the personal and educational use exceptions must be obtained from the copyright holderen_US
dc.subjectBee venom, formalin, hyperalgesia, hypersensitization, hot plate, inflammation, protanoids, sympathetic aminesen_US
dc.subject.lcshPain--Alternative treatmenten_US
dc.subject.lcshBee Venoms--Therapeutic useen_US
dc.subject.lcshUniversity of Balamand--Dissertationsen_US
dc.subject.lcshDissertations, Academicen_US
dc.titleEffect of bee venom on hyperalgesia hot-plate latencyen_US
dc.contributor.corporateUniversity of Balamanden_US
dc.contributor.departmentDepartment of Biologyen_US
dc.contributor.facultyFaculty of Arts and Sciencesen_US
dc.contributor.institutionUniversity of Balamanden_US
dc.description.degreeMSc in Biologyen_US
Appears in Collections:UOB Theses and Projects
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