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dc.contributor.advisorKaram, Marcen_US
dc.contributor.authorTayoun, Najiben_US
dc.descriptionIncludes bibliographical references (p. 41-54)en_US
dc.description.abstractAsthma is a long-term condition in which the bronchial airways in the lungs shrink and swell, making breathing difficult. Asthma is thought to be a disease caused by T helper 2 (Th2) cells which mainly causes the release of specific cytokines. These cytokines, which can produce many of the pro-inflammatory responses associated with asthma, play an important role in the coordination and persistence of the inflammatory process in chronic inflammation of the airways in asthma. Atherosclerosis is known as the buildup of lipids, cholesterol, and other chemicals in and on the walls of your arteries. Plaque is the term for this accumulation of lipids. The arteries may narrow because of the plaque, obstructing the blood flow. Cytokines which, have a major influence on disease progression, have been demonstrated to activate cells implicated in the pathogenesis of atherosclerosis. Anti-inflammatory cytokines slow the growth of atherosclerosis, while pro-inflammatory cytokines enhance it. New studies are targeting the common cytokines found in both diseases to find a correlation between the two. This study has shown that IL-4 could be an important factor in identifying a correlation between asthma and atherosclerosis. Moreover, identifying the plaque size after staining with Oil Red O by observing the lipid size in aorta and heart samples could give a boost for the evidence found in IL-4.en_US
dc.description.statementofresponsibilityby Najib Tayounen_US
dc.format.extent1 online resource (vii, 54 pages) : ill.en_US
dc.rightsThis object is protected by copyright, and is made available here for research and educational purposes. Permission to reuse, publish, or reproduce the object beyond the personal and educational use exceptions must be obtained from the copyright holderen_US
dc.subjectAsthma, Atherosclerosis, T helper 2 cells, IL-4, Plaque size, Oil Red Oen_US
dc.subject.lcshUniversity of Balamand--Dissertationsen_US
dc.subject.lcshDissertations, Academicen_US
dc.titleThe role of cytkokines [sic] cytokines in studying the correlation between asthma and atherosclerosis in mice : the effect of asthma on the cytokine profile and atherogenesis in miceen_US
dc.contributor.corporateUniversity of Balamanden_US
dc.contributor.departmentDepartment of Biologyen_US
dc.contributor.facultyFaculty of Arts and Sciencesen_US
dc.contributor.institutionUniversity of Balamanden_US
dc.description.degreeMSc in Biologyen_US
Appears in Collections:UOB Theses and Projects
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