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|Title:||Contribution of recurrent venous thrombosis and inherited thrombophilia to the pathogenesis of postthrombotic syndrome||Authors:||Kreidy, Raghid||Affiliations:||Faculty of Medicine||Keywords:||Deep vein thrombosis
|Issue Date:||2015||Publisher:||National Library of Medicine||Part of:||Clinical and Applied Thrombosis/Hemostasis||Volume:||21||Issue:||1||Start page:||87||End page:||90||Abstract:||
Postthrombotic syndrome (PTS) is a common complication of deep vein thrombosis. This study aims to assess the role of recurrent venous thrombosis and inherited thrombophilia in the pathogenesis of PTS. A series of 206 patients diagnosed with lower extremity venous thrombosis were retrospectively reviewed. The PTS was observed in 30.58% of the patients. Recurrent venous thrombosis was identified in 3.4% of the patients without PTS and in 33.3% of patients with PTS (P < .001). Inherited thrombophilia alone or in association with recurrent venous thrombosis was more commonly detected when PTS was moderate to severe (P = .04 and <.001) or severe (P < .001). Recurrent venous thrombosis increases the incidence of PTS significantly. The severity of PTS raises when an underlying thrombophilia is present either alone or in association with recurrent venous thrombosis.
|URI:||https://scholarhub.balamand.edu.lb/handle/uob/6039||ISSN:||10760296||DOI:||10.1177/1076029613497423||Ezproxy URL:||Link to full text||Type:||Journal Article|
|Appears in Collections:||Faculty of Medicine|
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