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Please use this identifier to cite or link to this item: https://scholarhub.balamand.edu.lb/handle/uob/6001
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dc.contributor.authorZerdan, Maroun Bouen_US
dc.contributor.authorHassan, Sally Alen_US
dc.contributor.authorShaker, Waleeden_US
dc.contributor.authorHajjar, Rayan Elen_US
dc.contributor.authorAllam, Sabineen_US
dc.contributor.authorZerdan, Morgan Bouen_US
dc.contributor.authorNaji, Amalen_US
dc.contributor.authorZeineddine, Nabilen_US
dc.date.accessioned2022-08-16T05:51:36Z-
dc.date.available2022-08-16T05:51:36Z-
dc.date.issued2022-07-
dc.identifier.issn19183003-
dc.identifier.urihttps://scholarhub.balamand.edu.lb/handle/uob/6001-
dc.description.abstractCarbapenem resistance, an emerging global health problem, compromises the treatment of infections caused by nosocomial pathogens. Preclinical and clinical trials demonstrate that a new generation of carbapenemases inhibitors, together with the recently approved avi-bactam, relebactam and vaborbactam, would address this resistance. Our review summarizes the latest developments related to carbap-enemase inhibitors synthesized to date, as well as their spectrum of activity and their current stage of development. A particular focus will be on β-lactam/β-lactamase inhibitor combinations that could potentially be used to treat infections caused by carbapenemase-producer pathogens. These new combinations mark a critical step forward the fight against antimicrobial resistance.en_US
dc.language.isoengen_US
dc.subjectCarbapenem resistanceen_US
dc.subjectCarbapenemase inhibitorsen_US
dc.subjectPathogensen_US
dc.titleCarbapenemase Inhibitors: Updates on Developments in 2021en_US
dc.typeJournal Articleen_US
dc.identifier.doi10.14740/jocmr4764-
dc.identifier.scopus2-s2.0-85135510296-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/85135510296-
dc.contributor.affiliationFaculty of Medicineen_US
dc.description.volume14en_US
dc.description.issue7en_US
dc.description.startpage251en_US
dc.description.endpage259en_US
dc.date.catalogued2022-08-16-
dc.description.statusPublisheden_US
dc.identifier.openURLhttps://www.jocmr.org/index.php/JOCMR/article/view/4764/25893586en_US
dc.relation.ispartoftextJournal of Clinical Medicine Researchen_US
dc.description.campusSGH campusen_US
Appears in Collections:Faculty of Medicine
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