Please use this identifier to cite or link to this item: https://scholarhub.balamand.edu.lb/handle/uob/5877
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dc.contributor.authorKhazaal, Shaymaaen_US
dc.contributor.authorHarb, Julienen_US
dc.contributor.authorRima, Mohamaden_US
dc.contributor.authorAnnweiler, Cédricen_US
dc.contributor.authorWu, Yingliangen_US
dc.contributor.authorCao, Zhijianen_US
dc.contributor.authorAbi Khattar, Ziaden_US
dc.contributor.authorLegros, Christianen_US
dc.contributor.authorKovacic, Hervéen_US
dc.contributor.authorFajloun, Ziaden_US
dc.contributor.authorSabatier, Jean-Marcen_US
dc.date.accessioned2022-07-14T09:41:27Z-
dc.date.available2022-07-14T09:41:27Z-
dc.date.issued2022-01-02-
dc.identifier.urihttps://scholarhub.balamand.edu.lb/handle/uob/5877-
dc.description.abstractCOVID-19 has expanded across the world since its discovery in Wuhan (China) and has had a significant impact on people's lives and health. Long COVID is a term coined by the World Health Organization (WHO) to describe a variety of persistent symptoms after acute SARS-CoV-2 infection. Long COVID has been demonstrated to affect various SARS-CoV-2-infected persons, independently of the acute disease severity. The symptoms of long COVID, like acute COVID-19, consist in the set of damage to various organs and systems such as the respiratory, cardiovascular, neurological, endocrine, urinary, and immune systems. Fatigue, dyspnea, cardiac abnormalities, cognitive and attention impairments, sleep disturbances, post-traumatic stress disorder, muscle pain, concentration problems, and headache were all reported as symptoms of long COVID. At the molecular level, the renin-angiotensin system (RAS) is heavily involved in the pathogenesis of this illness, much as it is in the acute phase of the viral infection. In this review, we summarize the impact of long COVID on several organs and tissues, with a special focus on the significance of the RAS in the disease pathogenesis. Long COVID risk factors and potential therapy approaches are also explored.en_US
dc.language.isoengen_US
dc.publisherNational Library of Medicineen_US
dc.subjectAngiotensin II receptor type 1en_US
dc.subjectAngiotensin II receptor type 2en_US
dc.subjectCOVID-19en_US
dc.subjectLong COVIDen_US
dc.subjectSARS-CoV-2en_US
dc.subjectAngiotensin-converting enzyme 2en_US
dc.subjectimmunity disordersen_US
dc.subjectInfectious diseaseen_US
dc.subjectRenin-angiotensin systemen_US
dc.titleThe Pathophysiology of Long COVID throughout the Renin-Angiotensin Systemen_US
dc.typeJournal Articleen_US
dc.identifier.doi10.3390/molecules27092903-
dc.identifier.pmid35566253-
dc.identifier.scopus2-s2.0-85130057082-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/85130057082-
dc.contributor.affiliationFaculty of Medicineen_US
dc.description.volume27en_US
dc.description.issue9en_US
dc.date.catalogued2022-07-14-
dc.description.statusPublisheden_US
dc.identifier.openURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101946/en_US
dc.relation.ispartoftextMoleculesen_US
dc.description.campusSGH campusen_US
Appears in Collections:Faculty of Medicine
Faculty of Medicine
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