Please use this identifier to cite or link to this item: https://scholarhub.balamand.edu.lb/handle/uob/5693
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dc.contributor.authorHage, Paulen_US
dc.contributor.authorKseib, Cedricen_US
dc.contributor.authorAdem, Carmenen_US
dc.contributor.authorChouairy, Camil Jen_US
dc.contributor.authorMatta, Revaen_US
dc.date.accessioned2022-06-02T07:27:14Z-
dc.date.available2022-06-02T07:27:14Z-
dc.date.issued2019-
dc.identifier.issn2210-2612-
dc.identifier.urihttps://scholarhub.balamand.edu.lb/handle/uob/5693-
dc.description.abstractIntroduction Currarino syndrome is a rare congenital disorder characterized by a triad of anorectal malformation, a sacral bone defect, and a presacral mass. It results of an abnormal separation of the ectoderm from the endoderm caused by HLXB9 mutation in chromosome 7q36 in 50% of cases. The disorder is mostly hereditary as it can also be sporadic with a variable expression spectrum. Presentation of Case The case of a previously healthy 3-month-old girl with abdominal distension, post-prandial vomiting, obstipation, and anuria of 5 days’ history is presented in this article. Abdomino-pelvic magnetic resonance imaging (MRI) showed a large cystic multilobulated mass in the sacrococcygeal region with a dural communication evident of an anterior sacral meningocele. 1 year later, the child came back with constipation and was found to a have a malignant mixed germ cell tumor in the presacral area, a very rare presentation in Currarino syndrome. Discussion In a child presenting with at least one of the features of Currarino syndrome’s triad, a diagnosis should be suspected. After reviewing the literature, the syndrome is usually missed and hence is under diagnosed. MRI is the best imaging modality for diagnostics and follow-up for any mass, benign or malignant, can bring life saving measures. Most masses are benign but can undergo malignant transformation even after resection. De novo malignancy is very rare and is described in our case. Conclusion Physicians treating patients with spinal dysraphism should suspect a diagnosis of Currarino syndrome by follow up imaging for any new benign or malignant growth.en_US
dc.language.isoengen_US
dc.publisherNational Library of Medicineen_US
dc.subjectCase reporten_US
dc.subjectCurrarino syndromeen_US
dc.subjectDysraphismen_US
dc.subjectMalignancyen_US
dc.subjectNeurosurgeryen_US
dc.subjectPediatric surgeryen_US
dc.titleAtypical presentation of currarino syndrome: A case reporten_US
dc.typeJournal Articleen_US
dc.identifier.doi10.1016/j.ijscr.2019.02.047-
dc.identifier.pmid30933899-
dc.identifier.scopus2-s2.0-85063523386-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/85063523386-
dc.contributor.affiliationFaculty of Medicineen_US
dc.description.volume57en_US
dc.description.startpage102en_US
dc.description.endpage105en_US
dc.date.catalogued2022-05-02-
dc.description.statusPublisheden_US
dc.identifier.openURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441767/en_US
dc.relation.ispartoftextInternational Journal of Surgery Case Reportsen_US
dc.description.campusSGH campusen_US
Appears in Collections:Faculty of Medicine
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