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dc.contributor.authorRoest, Annelieke Men_US
dc.contributor.authorde Vries, Ymkje Annaen_US
dc.contributor.authorAl-Hamzawi, Alien_US
dc.contributor.authorAlonso, Jordien_US
dc.contributor.authorAyinde, Olatunde Oen_US
dc.contributor.authorBruffaerts, Ronnyen_US
dc.contributor.authorBunting, Brendanen_US
dc.contributor.authorCaldas de Almeida, José Miguelen_US
dc.contributor.authorde Girolamo, Giovannien_US
dc.contributor.authorDegenhardt, Louisaen_US
dc.contributor.authorFlorescu, Silviaen_US
dc.contributor.authorGureje, Oyeen_US
dc.contributor.authorHaro, Josep Mariaen_US
dc.contributor.authorHu, Chiyien_US
dc.contributor.authorKaram, Elie G.en_US
dc.contributor.authorKiejna, Andrzejen_US
dc.contributor.authorKovess-Masfety, Vivianeen_US
dc.contributor.authorLee, Singen_US
dc.contributor.authorMcGrath, John Jen_US
dc.contributor.authorMedina-Mora, Maria Elenaen_US
dc.contributor.authorNavarro-Mateu, Fernandoen_US
dc.contributor.authorNishi, Daisukeen_US
dc.contributor.authorPiazza, Marinaen_US
dc.contributor.authorPosada-Villa, Joséen_US
dc.contributor.authorScott, Kate Men_US
dc.contributor.authorStagnaro, Juan Carlosen_US
dc.contributor.authorStein, Dan Jen_US
dc.contributor.authorTorres, Yolandaen_US
dc.contributor.authorViana, Maria Carmenen_US
dc.contributor.authorZarkov, Zaharien_US
dc.contributor.authorKessler, Ronald Cen_US
dc.contributor.authorde Jonge, Peteren_US
dc.description.abstractAims Major depressive disorder (MDD) is characterised by a recurrent course and high comorbidity rates. A lifespan perspective may therefore provide important information regarding health outcomes. The aim of the present study is to examine mental disorders that preceded 12-month MDD diagnosis and the impact of these disorders on depression outcomes. Methods Data came from 29 cross-sectional community epidemiological surveys of adults in 27 countries (n = 80 190). The Composite International Diagnostic Interview (CIDI) was used to assess 12-month MDD and lifetime DSM-IV disorders with onset prior to the respondent's age at interview. Disorders were grouped into depressive distress disorders, non-depressive distress disorders, fear disorders and externalising disorders. Depression outcomes included 12-month suicidality, days out of role and impairment in role functioning. Results Among respondents with 12-month MDD, 94.9% (s.e. = 0.4) had at least one prior disorder (including previous MDD), and 64.6% (s.e. = 0.9) had at least one prior, non-MDD disorder. Previous non-depressive distress, fear and externalising disorders, but not depressive distress disorders, predicted higher impairment (OR = 1.4–1.6) and suicidality (OR = 1.5–2.5), after adjustment for sociodemographic variables. Further adjustment for MDD characteristics weakened, but did not eliminate, these associations. Associations were largely driven by current comorbidities, but both remitted and current externalising disorders predicted suicidality among respondents with 12-month MDD. Conclusions These results illustrate the importance of careful psychiatric history taking regarding current anxiety disorders and lifetime externalising disorders in individuals with MDD.en_US
dc.subjectMajor depressive disorderen_US
dc.subjectSuicidal thoughts and behavioursen_US
dc.titlePrevious disorders and depression outcomes in individuals with 12-month major depressive disorder in the World Mental Health surveysen_US
dc.typeJournal Articleen_US
dc.contributor.affiliationFaculty of Medicineen_US
dc.relation.ispartoftextEpidemiology Psychiatric Sciencesen_US
dc.description.campusSGH campusen_US
Appears in Collections:Faculty of Medicine
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