Please use this identifier to cite or link to this item: https://scholarhub.balamand.edu.lb/handle/uob/2498
DC FieldValueLanguage
dc.contributor.authorJamsheer, A.en_US
dc.contributor.authorRafay, A. M.en_US
dc.contributor.authorTorumkuney, D.en_US
dc.contributor.authorDaoud, Ziaden_US
dc.contributor.authorMorrissey, I.en_US
dc.date.accessioned2020-12-23T09:14:29Z-
dc.date.available2020-12-23T09:14:29Z-
dc.date.issued2016-
dc.identifier.urihttps://scholarhub.balamand.edu.lb/handle/uob/2498-
dc.description.abstractObjectives To provide surveillance data on the susceptibility of community-acquired respiratory tract isolates from four Gulf and Near East countries from 2011 to 2013. Methods MICs were determined using Etests® for all antibiotics evaluated except erythromycin, where testing was by disc diffusion. Susceptibility was assessed using CLSI, EUCAST and pharmacokinetic/pharmacodynamic (PK/PD) breakpoints. Results Seven hundred and twenty-six respiratory isolates comprising 265 isolates of Streptococcus pneumoniae, 125 isolates of Streptococcus pyogenes and 336 isolates of Haemophilus influenzae were collected from Bahrain, Lebanon, Oman and the United Arab Emirates (UAE). Among S. pneumoniae, susceptibility to penicillin was low in the UAE and Bahrain. Macrolide susceptibility was ∼45%–60% in the UAE and Oman but higher in Lebanon (73.7%) and Bahrain (84%–85%). Penicillin susceptibility using CLSI intravenous breakpoints was >85% in all countries. Antibiotic susceptibility of S. pneumoniae was lower in UAE and Oman. Among S. pyogenes isolates, resistance to erythromycin was highest in Oman (31.6%) but <20% in the other countries. In H. influenzae, susceptibility to most antibiotics was high, except for ampicillin in Lebanon (70.2%) and amoxicillin in Oman (95.4%). Lebanon also had a high percentage (14.9%) of β-lactamase-positive isolates with non-susceptibility to ampicillin. Amoxicillin/clavulanic acid susceptibility was >95% in all countries. Use of EUCAST versus CLSI breakpoints demonstrated profound differences for cefaclor and cefuroxime in S. pneumoniae and H. influenzae, with EUCAST showing lower susceptibility. Conclusions There was considerable variability in susceptibility among countries in the same region. Thus, continued surveillance is necessary to track future changes in antibiotic resistance.en_US
dc.format.extent16 p.en_US
dc.language.isoengen_US
dc.subjectAmoxicillinen_US
dc.subjectAmpicillinen_US
dc.subjectCeftriaxoneen_US
dc.subjectErythromycinen_US
dc.subjectAzithromycinen_US
dc.subjectStreptococcus pyogenesen_US
dc.subjectAntibiotic resistanceen_US
dc.subjectBacterialen_US
dc.subjectPenicillinen_US
dc.subjectcefepimeen_US
dc.subjectcefuroximeen_US
dc.subjectCiprofloxacinen_US
dc.subjectClarithromycinen_US
dc.subjectDiffusionen_US
dc.subjectHaemophilus influenzaeen_US
dc.subjectamoxicillin-potassium clavulanate combinationen_US
dc.subjectBahrainen_US
dc.subjectcefacloren_US
dc.subjectcefiximeen_US
dc.subjectOmanen_US
dc.subjectStreptococcus pneumoniaeen_US
dc.subjectUnited Arab Emiratesen_US
dc.subjectmacrolidesen_US
dc.subjectlevofloxacinen_US
dc.subjectpharmacodynamicsen_US
dc.subjectmoxifloxacinen_US
dc.subjectAntimicrobial agentsen_US
dc.subjectAntimicrobial susceptibilityen_US
dc.subjectcefpodoximeen_US
dc.subjectsurveillance, medicalen_US
dc.subjectmulti-antibiotic resistanceen_US
dc.subjectmalnutrition-inflammation-cachexia syndromeen_US
dc.subject.lcshAntibioticsen_US
dc.subject.lcshCommunityen_US
dc.subject.lcshLebanonen_US
dc.titleResults from the survey of antibiotic resistance (SOAR) 2011-13 in the gulf statesen_US
dc.typeJournal Articleen_US
dc.contributor.affiliationFaculty of Medicineen_US
dc.description.volume71en_US
dc.description.issue1en_US
dc.description.startpagei45en_US
dc.description.endpagei61en_US
dc.date.catalogued2017-12-18-
dc.description.statusPublisheden_US
dc.identifier.OlibID175688-
dc.identifier.openURLhttps://academic.oup.com/jac/article/71/suppl_1/i45/2488558?searchresult=1en_US
dc.relation.ispartoftextJournal of antimicrobial chemotherapyen_US
dc.provenance.recordsourceOliben_US
Appears in Collections:Faculty of Medicine
Show simple item record

Record view(s)

2
checked on Nov 28, 2021

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.