Please use this identifier to cite or link to this item: https://scholarhub.balamand.edu.lb/handle/uob/1771
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dc.contributor.authorSalma, Yahyaen_US
dc.contributor.authorZakaria, Hassanen_US
dc.contributor.authorHassan, Inas ELen_US
dc.contributor.authorBouchekara, Mohammaden_US
dc.contributor.authorNakat, Hanna Elen_US
dc.contributor.authorOmar, Fawaz Elen_US
dc.contributor.authorAllouch, Ahmaden_US
dc.date.accessioned2020-12-23T08:59:40Z-
dc.date.available2020-12-23T08:59:40Z-
dc.date.issued2018-
dc.identifier.urihttps://scholarhub.balamand.edu.lb/handle/uob/1771-
dc.description.abstractThe activity of a chiral molecule can vary from one atropisomer to the other. In this study, the separation of racemic-N-(2-methylphenyl), N-(2-chlorophenyl) thiourea (H2L2), a hydrophobic heavy metal trap, has been studied using reversed-phase high-performance liquid chromatography (RP-HPLC) with hydroxypropyl-beta-cyclodextrin (HP-β-CD) as a complexing additive to the racemic mixture and hexane-isopropanol as a mobile phase. The stoichiometry and the overall association constant of the complex have been determined using the continuous variation (Job's plot) method and the Scott's method respectively.en_US
dc.format.extent6 p.en_US
dc.language.isoengen_US
dc.subjectThioureaen_US
dc.subjectHP-Beta-CDen_US
dc.subjectHPLCen_US
dc.subjectAtropisomeric separationen_US
dc.subjectInclusion complexesen_US
dc.titleComplex of a new racemic thiourea substrate : Spectrophotometric study and separation of atropisomersen_US
dc.typeJournal Articleen_US
dc.contributor.affiliationDepartment of Chemistryen_US
dc.description.volume8en_US
dc.description.issue1en_US
dc.description.startpage1en_US
dc.description.endpage6en_US
dc.date.catalogued2019-05-31-
dc.description.statusPublisheden_US
dc.identifier.OlibID192235-
dc.identifier.openURLhttps://ssjournals.com/index.php/ijpc/article/view/4681en_US
dc.relation.ispartoftextInternational journal of pharmaceutical chemistryen_US
dc.provenance.recordsourceOliben_US
Appears in Collections:Department of Chemistry
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